Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 3.168


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXB6chr17_-_440373320.674.2e-03Click!
HOXA7chr7_-_271626880.302.6e-01Click!
HOXB7chr17_-_440429240.253.4e-01Click!
HOXA6chr7_-_271538920.185.0e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_14076901 27.281 NFIB
nuclear factor I/B
chr3_+_161040439 16.538 SCHIP1
schwannomin interacting protein 1
chr3_+_161040343 14.821 NM_001197109
 SCHIP1
schwannomin interacting protein 1
chr2_+_101874809 13.737 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_+_160269734 13.710 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr2_+_101874765 12.469 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_135079461 12.037 NM_001167819
 FHL1
four and a half LIM domains 1
chr12_-_90100710 12.009 DCN
decorin
chr12_-_90100733 10.551 NM_001920
 DCN
decorin
chr2_-_215967442 10.507 FN1
fibronectin 1
chr12_-_90100679 10.460 DCN
decorin
chr5_+_71538456 10.282 MAP1B
microtubule-associated protein 1B
chr2_-_215949566 10.048 FN1
fibronectin 1
chr10_-_126706442 9.906 NM_022802
 CTBP2
C-terminal binding protein 2
chrX_+_135106578 9.882 NM_001159701
NM_001159699
 FHL1

four and a half LIM domains 1

chr13_-_37070862 9.367 NM_001135934
NM_001135935
NM_001135936
NM_006475
 POSTN



periostin, osteoblast specific factor



chr9_+_96561750 9.364 NM_001193329
 C9orf3
chromosome 9 open reading frame 3
chrX_+_135079120 9.244 NM_001159704
 FHL1
four and a half LIM domains 1
chr21_-_26175068 8.795 APP
amyloid beta (A4) precursor protein
chr7_-_41709191 8.742 NM_002192
 INHBA
inhibin, beta A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 75 entries
enrichment   p-value GO term description
2.94 6.21e-03 GO:0051781 positive regulation of cell division
2.68 2.58e-04 GO:0022612 gland morphogenesis
2.68 3.17e-03 GO:0007519 skeletal muscle tissue development
2.64 8.41e-09 GO:0007156 homophilic cell adhesion
2.58 4.98e-02 GO:0051302 regulation of cell division
2.54 1.06e-02 GO:0060538 skeletal muscle organ development
2.50 4.02e-03 GO:0048706 embryonic skeletal system development
2.22 9.95e-04 GO:0014706 striated muscle tissue development
2.18 6.46e-04 GO:0060537 muscle tissue development
2.04 2.53e-03 GO:0043062 extracellular structure organization
1.98 1.78e-02 GO:0034330 cell junction organization
1.97 7.82e-07 GO:0016337 cell-cell adhesion
1.93 2.14e-03 GO:0048732 gland development
1.90 8.93e-03 GO:0008544 epidermis development
1.88 8.13e-06 GO:0001501 skeletal system development
1.83 3.39e-04 GO:0061061 muscle structure development
1.83 2.33e-02 GO:0007517 muscle organ development
1.79 3.05e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.76 4.87e-02 GO:0003002 regionalization
1.72 1.14e-10 GO:0007155 cell adhesion

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.26 9.86e-04 GO:0030017 sarcomere
2.16 8.98e-04 GO:0044449 contractile fiber part
2.15 7.03e-04 GO:0030016 myofibril
2.07 1.58e-03 GO:0043292 contractile fiber
1.98 2.40e-02 GO:0044420 extracellular matrix part
1.90 1.66e-06 GO:0005578 proteinaceous extracellular matrix
1.73 4.34e-05 GO:0031012 extracellular matrix
1.72 5.28e-03 GO:0016323 basolateral plasma membrane
1.35 2.08e-03 GO:0044421 extracellular region part
1.26 1.29e-03 GO:0005576 extracellular region
1.22 9.74e-07 GO:0005886 plasma membrane
1.21 1.87e-06 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.42 1.96e-03 GO:0005201 extracellular matrix structural constituent
2.03 2.21e-04 GO:0008083 growth factor activity
1.61 2.29e-02 GO:0032403 protein complex binding
1.57 5.56e-06 GO:0005509 calcium ion binding
1.53 3.64e-05 GO:0043565 sequence-specific DNA binding
1.42 1.22e-04 GO:0001071 nucleic acid binding transcription factor activity
1.42 1.22e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 3.73e-02 GO:0005198 structural molecule activity
1.36 1.27e-03 GO:0005102 receptor binding
1.35 6.93e-03 GO:0030528 transcription regulator activity